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STEMCELL Technologies Inc
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ChemieTek LLC
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ApexBio
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Novartis
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Image Search Results
Journal: RSC Advances
Article Title: Beneficial roles of the AhR ligand FICZ on the regenerative potentials of BMSCs and primed cartilage templates
doi: 10.1039/d2ra00622g
Figure Lengend Snippet: Effects of FICZ or SR1 on proliferation, osteogenic differentiation, cell migration and inflammatory responses of the cultured BMSCs. (a) The absorbance at 450 nm of the CCK8 assay of the BMSCs. The number of viable BMSCs increased in all groups and there were no significant differences among the three groups on days 0, 1, 3 and 5 ( p < 0.05). (b) ALP staining (upper) and ARS staining (lower) showed a stimulative effect of FICZ and inhibitory effect of SR1 on the osteogenic differentiation of BMSCs. (c) RT-PCR demonstrated that FICZ or SR1 prevented or exacerbated LPS-induced IL-1β, 6 and TNF-α, respectively (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001).
Article Snippet: BMSCs were seeded in 96-well plate (1 × 10 3 cells per well) and incubated in a culture medium containing 500 nM FICZ (CAS No. 172922-91-7) (HY-12451, MCE), 1 μM
Techniques: Migration, Cell Culture, CCK-8 Assay, Staining, Reverse Transcription Polymerase Chain Reaction